جامعة الكوت - University of kut

السنة	عنوان البحث	نشر البحث
2026	Pediatric Antimicrobial Resistance in Iraq: Epidemiology and Silver Nanoparticle Synergy	Journal of Nanostructures
Antimicrobial resistance (AMR) is a worldwide problem impacting on pediatric health, especially in low-resource areas. The present study is a cross-sectional surveillance to describe bacterial pathogens and their resistance patterns in 200 children (0–12 years) attending to three hospitals in Wasit Governorate, Iraq during January 2022 - December 2024. The most common microorganisms were Escherichia coli (29%) and Klebsiella pneumoniae (21%). The proportion of ampicillin resistant organisms (APCs) was 74%, whereas those with carbapenems were still 92% susceptible. Multidrug-resistant (MDR) organisms comprised 30.5% of isolates, escalating significantly from 26.3% (2022) to 44.4% (2024) (p=0.033). ESBL production was seen 19% of the time, and the most prevalent was seen in neonates (66.7%). Silver nanoparticles (AgNPs) were synthesized by green reduction method and characterized by the UV-Vis, XRD and SEM. The results showed a significant 8-fold decrease in the MIC of ampicillin for MRSA and 4–16-fold decrease in MIC of vancomycin for VRE when tested by synergy testing using AgNPs. MDR management in resource-limited pediatric settings is promising to be aided with nanotechnology as an adjunctive therapy.

اسامة اسماعيل فرحان الركابي