مسار بولونيا
AR

وسام باسم محمد التميمي

السنة عنوان البحث نشر البحث
2024 The Role Of Sperm DNA Fragmentation On Male Infertility In Al Kut City Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Abstract. Infertility is one of the most common diseases in the world in last period of all types, whether it is due to (asthenospermia,oligoasthenospermia,teratospermia,hormonal imbalance). Study aims to reveal negative effect of sperm DNA fragmentation on fertilization, this study was conducted in the Al-Jazeera Specialized Laboratory in the city of Kut for the period between (January to November from 2024), two hundred A person suffering from infertility. The semen was examined for all of them, they were divided into eighty of them being normal (the control group) and one hundred and twenty suffering from infertility (asthenospermia) hormonal test and sperm DNA fragmentation test (by Kit methods) was performed for everyone , this study showed Following, we obtained higher proportions of sperm DNA fragmented infertile Which had an abnormal shape and low motility. The results are similar to those of other studies, which found that the DFI in infertile group was significantly higher than that in fertile group (34.53 ± 4.6 % compared to11.91 ± 4.0 %) and mean sperm concentration in fertile group was significantly higher compared to infertile group (83.22 ± 14.9 /ml compared to11.67 ± 10.7 /ml) from this study. Through this study, the DFI test they can be used for discrimination and between the infertile male and normal male . Male men with sperm (DFI ≥ 25.1% ) had a (2.52 ) times higher risk of infertility compared to males with sperm (DFI < 25.1%). This study shows that there is a negative relationship between (spem DNA fragmentation , sperm motility and formation) in infertile males. In addition, it can be concluded that sperm DNA fragmentation is very useful in selecting and choosing suitable sperm to be used in many techniques, including assisted reproductive techniques. It can also be concluded that the results of sperm DNA fragmentation analysis are encouraging and useful and can be used for diagnostic purposes in determining male infertility