جامعة الكوت - University of kut - Research Fatima sinan salman

	2022	International Journal of Health Sciences
The aim of this prospective study is to evaluate the effect of using N-acetyl cysteine (600mg/day) for 3 consecutive months on the serum level of total antioxidant capacity of Iraqi males with idiopathic infertility. This study was performed at infertile center of ALKUT hospital during the period from October 2021 to March 2022 .A total 45 patients with idiopathic oligoasthenoteratozoospermia were received N-acetyl cysteine (NAC) for 12 weeks, their total antioxidant capacity (TAC) was measured at the baseline and after 12 weeks. The results showed that TAC levels were significantly higher (0.61±0.02 vs. 0.86±0.02 ; LSD= 0.10 ) which confirmed that NAC has positive effect in increasing the level of antioxidant capacity in infertile men and thus decreasing the reactive oxygen species ROS and restore the oxidant balance level resulting in better spermatogenesis and sperm function

	2022	J Fac Med Baghdad
Background : infertility is recognised as the incapability of infertile couples to become pregnant following one year of unsafe intercourse, with male factors accounting for roughly half of the documented instances. Several reasons of male infertility factors have been reported; however, the actual cause in the majority of cases remains unknown. Objective: To study prospectively the outcome of N-acetylcysteine on semen parameters in males with oligoasthenoteratozoospermia. Patient and methods: A total 45 patients with idiopathic oligoasthenoteratozoospermia have received N- acetyl cysteine (NAC) for 12 weeks, their seminal fluid parameters were measured at the baseline and after 12 weeks. Results: The results showed that after 3 months of NAC treatment, the motility was statistically significantly higher than pre-NAC baseline, with no statistically significant differences in both count and morphology. Conclusion: These results confirmed that NAC has a positive effect in improving motility in infertile men and thus resulting in better spermatogenesis and sperm function.